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Lab Research2020-12-27T03:36:08+00:00

Toxins

In the Melnyk lab, we study a group of proteins known as toxins. These remarkable proteins, which include notable examples such as diphtheria toxin, botulinum toxin or C. difficile toxin B are among the most toxic molecules to humans known and are often responsible for the symptoms of their associated diseases Diphtheria, Botulism or Pseudomembranous colitis, respectively. We are interested in these molecules for a number of reasons, ranging from using these as model systems to understand how proteins cross membranes, to developing small molecule inhibitors to block their function, to engineering these proteins to deliver protein therapeutics into cells.

  • Toxin structure & function – cras vlutpat oho ac saen faucibus auct

  • Small molecule inhibitors of toxin function – Sed consuat odio quis dicum

  • Engineering toxins as intracellular drug delivery platforms – Nam ac pharra nibh. Nulam eu mna sit

 

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Testing

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